uncertR: Bootstrap Prediction Uncertainty and Its Biological Drivers in
Gene-Expression Models
Fits bootstrap ensembles of penalized regression models on bulk
gene-expression data, derives per-sample uncertainty scores from
out-of-bag predictions, and tests whether technical covariates explain that
uncertainty. The bootstrap method is described by Efron and Tibshirani
(1993, ISBN:9780412042317), and elastic-net regression follows Friedman,
Hastie, and Tibshirani (2010) <doi:10.18637/jss.v033.i01>.
The optional immunedeconv package, used for immune-cell deconvolution, is available from GitHub <https://github.com/omnideconv/immunedeconv>.
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