rxode2lincmt: Linear Compartment Model Solutions and Gradients for 'rxode2'
Analytic one, two and three compartment linear pharmacokinetic
solutions with their parameter gradients from 'stan' automatic
differentiation (Carpenter et al (2015) <doi:10.48550/arXiv.1509.07164>),
eigen decompositions and derived-parameter conversions used by 'rxode2'
(Wang, Hallow and James (2016) <doi:10.1002/psp4.12052>). Split out of
'rxode2' so its installation does not compile 'stan' AD items which made it
take too long to compile by itself.
The closed-form solutions follow the idea of the 'wnl' package
(Bae, <https://CRAN.R-project.org/package=wnl>), though the
implementation here is different.
| Version: |
0.1.0 |
| Depends: |
R (≥ 4.1.0) |
| Imports: |
Rcpp (≥ 1.0.8), checkmate |
| LinkingTo: |
Rcpp (≥ 1.0.8), RcppEigen (≥ 0.3.3.9.2), StanHeaders (≥
2.21.0.7), BH, RcppParallel |
| Suggests: |
covr, testthat (≥ 3.0.0) |
| Published: |
2026-09-24 |
| DOI: |
10.32614/CRAN.package.rxode2lincmt (may not be active yet) |
| Author: |
Matthew L. Fidler 
[aut, cre],
Richard Upton [ctb] |
| Maintainer: |
Matthew L. Fidler <matthew.fidler at gmail.com> |
| BugReports: |
https://github.com/nlmixr2/rxode2lincmt/issues/ |
| License: |
GPL (≥ 3) |
| URL: |
https://nlmixr2.github.io/rxode2lincmt/,
https://github.com/nlmixr2/rxode2lincmt/ |
| NeedsCompilation: |
yes |
| Language: |
en-US |
| Materials: |
README, NEWS |
| CRAN checks: |
rxode2lincmt results |
Documentation:
Downloads:
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