POEMED: Power Enhancement for High-Dimensional Mediation Analysis
Provides powerful global tests for high-dimensional mediation analysis with heterogeneous (and even contrasting) mediation effects, for continuous, binary, and count outcomes. The power enhancement (PE) idea augments a Wald test on the total indirect effect with a component that captures marginal signals from individual mediators, so that active mediators are detected even when their individual indirect effects cancel and the total indirect effect is zero. The package also identifies which individual mediators are active with familywise error rate or false discovery rate control. The methods implement Yu and Kelley (in press), "Power Enhancement in High-Dimensional Heterogeneous Mediation Analysis" (Journal of the American Statistical Association); the package also simulates mediation data under the homogeneous, heterogeneous, and contrasting patterns that the article studies, ships its empirical health-expenditure data as a benchmark and reruns that empirical analysis, and runs the designs of its Monte Carlo size and power studies. The name, 'POEMED', from POwer-Enhanced MEDiation, encodes the method. Every estimation and testing function returns a tidy 'data.frame' that prints with sensible rounding and composes with the broader R ecosystem.
| Version: | 1.0.0 |
| Depends: | R (≥ 4.1.0) |
| Imports: | generics, glmnet, graphics, ncvreg, parallel, stats, utils, withr (≥ 3.0.3) |
| Suggests: | knitr, rmarkdown, testthat (≥ 3.2.0), tools |
| Published: | 2026-10-18 |
| DOI: | 10.32614/CRAN.package.POEMED (may not be active yet) |
| Author: | Xiufan Yu [aut],
Ken Kelley  [aut,
cre] |
| Maintainer: | Ken Kelley <kkelley at nd.edu> |
| BugReports: | https://github.com/yelleKneK/POEMED/issues |
| License: | GPL (≥ 3) |
| Copyright: | Xiufan Yu and Ken Kelley, except the WHO_health_mediation and WHO_indicator_codebook data sets, which redistribute World Health Organization (Global Health Expenditure Database) and World Bank (World Development Indicators) data under the terms stated on the help page of WHO_health_mediation and, in the source package, in the file LICENSE.note. |
| URL: | https://github.com/yelleKneK/POEMED, https://yelleknek.github.io/POEMED/ |
| NeedsCompilation: | no |
| Language: | en-US |
| Citation: | POEMED citation info |
| Materials: | README, NEWS |
| CRAN checks: | POEMED results |
Documentation:
Downloads:
| Package source: | POEMED_1.0.0.tar.gz |
| Windows binaries: | r-devel: not available, r-release: not available, r-oldrel: not available |
| macOS binaries: | r-release (arm64): not available, r-oldrel (arm64): not available, r-release (x86_64): not available, r-oldrel (x86_64): not available |
Linking:
Please use the canonical form https://CRAN.R-project.org/package=POEMED to link to this page.